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Microbe-Powered Jobs: How Microbiologists Can Help Build the Bioeconomy

Microbe-Powered Jobs: How Microbiologists Can Help Build the Bioeconomy

    Microbes can be highly efficient, versatile and sophisticated manufacturing tools, and have the potential to form the basis of a vibrant economic sector. In order to take full advantage of...

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FAQ: Human Microbiome, January 2014

FAQ: Human Microbiome, January 2014

  The human microbiome, the collection of trillions of microbes living in and on the human body, is not random, and scientists believe that it plays a role in many...

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How Microbes Can Help Feed the World, 2013

How Microbes Can Help Feed the World, 2013

    "How Microbes can Help Feed the World" looks in depth at the intimate relationship between microbes and agriculture including why plants need microbes, what types of microbes they need, how...

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FAQ: West Nile Virus, July 2013

FAQ: West Nile Virus, July 2013

   Where does the virus come from? How is it spread? Can we predict when and where outbreaks will occur? What factors determine how sick a person will become if they...

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FAQ: Influenza, April 2013

FAQ: Influenza, April 2013

   Where do new influenza viruses come from? How are they different from the influenza viruses that circulate every year? Why is vaccination so important? To help answer the many questions...

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Cubist-ICAAC Award 
April 1, 2014

ICAAC Young Investigator Awards 
April 1, 2014

asm2015 Awards 
July 1, 2014

 

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Congratulations to the 2014 Academy Fellows!

mBio™

mBio imagemBio™ is ASM's first broad-scope, online-only, open-access journal. It is published in association with the American Academy of Microbiology.


mBio™ home page
   |   mBio™ for Fellows

csonka laszlo

His laboratory studies the responses of cells to high salinity stress. A sudden increase in the external osmolality causes rapid efflux of water from the cells. The ability to adapt to changes in the external osmolality is a fundamental response in cell physiology that is highly conserved across all biological kingdoms. Hisresearch is concentrated on three areas of osmotic regulation. First, the exposure of the food poisoning bacterium Salmonella to moderate or high salinity renders this organism more tolerant of high temperature stress. He is studying the interaction between salinity stress adaptation and high temperature tolerance. This research will provide insights into conditions that increase the efficacy of inactivation of Salmonella in food products by high temperature. He found that proline overproduction confers increased resistance to high salinity stress in Salmonella and other bacteria. The proline-overproducing mutations decreased the sensitivity of g -glutamyl kinase (the first enzyme of proline synthesis) to allosteric inhibition by proline. He is carrying experiments to characterize the enzymological properties and three-dimensional structure the wild type and mutant of g -glutamyl kinases. Better understanding of this enzyme might make it possible to engineer proline overproducing, salt tolerant derivatives of agronomic plants. Finally, he is carrying out physiological and genomic analyses of the bacterium Chromohalobacter salexigens . This bacterium is unusual because it grows optimally in highly saline environments that are lethal to most other organisms. The study of the basis for the exceptional salt stress tolerance of this organism might make it possible to develop it for use in remediation of toxic environments of high salinity.


Website: http://www.bio.purdue.edu/people/faculty/index.php?refID=21 


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